וְאֵ֛לֶּה תּוֹלְדֹ֥ת יִצְחָ֖ק בֶּן־אַבְרָהָ֑ם אַבְרָהָ֖ם הוֹלִ֥יד אֶת־יִצְחָֽק׃
This is the story of Isaac, son of Abraham. Abraham begot Isaac.
אברהם הוליד את יצחק.עַל יְדֵי שֶׁכָּתַב הַכָּתוּב יִצְחָק בֶּן אַבְרָהָם הֻזְקַק לוֹמַר אַבְרָהָם הוֹלִיד אֶת יִצְחָק; לְפִי שֶׁהָיוּ לֵיצָנֵי הַדּוֹר אוֹמְרִים מֵאֲבִימֶלֶךְ נִתְעַבְּרָה שָׂרָה, שֶׁהֲרֵי כַּמָּה שָׁנִים שָׁהֲתָה עִם אַבְרָהָם וְלֹא נִתְעַבְּרָה הֵימֶנּוּ; מֶה עָשָׂה הַקָּבָּ"ה? צָר קְלַסְתֵּר פָּנָיו שֶׁל יִצְחָק דּוֹמֶה לְאַבְרָהָם, וְהֵעִידוּ הַכֹּל אַבְרָהָם הוֹלִיד אֶת יִצְחָק, וְזֶהוּ שֶׁכָּתוּב כָּאן יִצְחָק בֶּן אַבְרָהָם, שֶׁהֲרֵי עֵדוּת יֵשׁ שֶׁאַבְרָהָם הוֹלִיד אֶת יִצְחָק:
אברהם הוליד את יצחק ABRAHAM BEGAT ISAAC — Just because Scripture wrote, “Isaac, son of Abraham” it felt compelled to say “Abraham begat Isaac”, because the cynics of that time said, “Sarah became with child of Abimelech. See how many years she lived with Abraham without becoming with child”. What did the Holy One, blessed be He, do? He shaped Isaac’s facial features exactly similar to those of Abraham’s, so that everyone had to admit that Abraham begat Isaac. This is what is stated here: that Isaac was the son of Abraham, for there is evidence that Abraham begat Isaac (Midrash Tanchuma, Toldot 1).
וַיִּתְרֹֽצְצ֤וּ הַבָּנִים֙ בְּקִרְבָּ֔הּ וַתֹּ֣אמֶר אִם־כֵּ֔ן לָ֥מָּה זֶּ֖ה אָנֹ֑כִי וַתֵּ֖לֶךְ לִדְרֹ֥שׁ אֶת־יהוה׃
But the children struggled in her womb, and she said, “If so, why do I exist?” She went to inquire of יהוה,
ויתרוצצו. עַ"כָּ הַמִּקְרָא הַזֶּה אוֹמֵר דָּרְשֵׁנִי, שֶׁסָּתַם מַה הִיא רְצִיצָה זוֹ וְכָתַב אִם כֵּן לָמָּה זֶּה אָנֹכִי? רַבּוֹתֵינוּ דְּרָשׁוּהוּ לְשׁוֹן רִיצָה; כְּשֶׁהָיְתָה עוֹבֶרֶת עַל פִּתְחֵי תּוֹרָה שֶׁל שֵׁם וָעֵבֶר יַעֲקֹב רָץ וּמְפַרְכֵּס לָצֵאת, עוֹבֶרֶת עַל פֶּתַח עֲבוֹדַת אֱלִילִים, עֵשָׂו מְפַרְכֵּס לָצֵאת. דָּבָר אַחֵר מִתְרוֹצְצִים זֶה עִם זֶה וּמְרִיבִים בְּנַחֲלַת שְׁנֵי עוֹלָמוֹת.
ויתרצצו AND [THE CHILDREN] STRUGGLED — You must admit that this verse calls for a Midrashic interpretation since it leaves unexplained what this struggling was about and it states that she exclaimed “If it be so, wherefore did I desire this” (i.e. she asked whether this was the normal course of child-bearing, feeling that something extraordinary was happening). Our Rabbis explain that the word ויתרוצצו has the meaning of running, moving quickly: whenever she passed by the doors of the Torah (i. e. the Schools of Shem and Eber) Jacob moved convulsively in his efforts to come to birth, but whenever she passed by the gate of a pagan temple Esau moved convulsively in his efforts to come to birth (Genesis Rabbah 63:6). Another explanation is: they struggled with one another and quarrelled as to how they should divide the two worlds as their inheritance (Yalkut Shimoni on Torah 111:2).
(כד) וַיִּמְלְא֥וּ יָמֶ֖יהָ לָלֶ֑דֶת וְהִנֵּ֥ה תוֹמִ֖ם בְּבִטְנָֽהּ׃
(24) When her time to give birth was at hand, there were twins in her womb.
When a word is written without a letter (usually a vav functioning as a holem, but not always, but not always This feature is often an occasion for a drash in both the rabbinic lit and for Rashi. In these drashot, the חסר form points to something missing.
והנה תומם. חָסֵר, וּבְתָמָר תְּאוֹמִים מָלֵא, לְפִי שֶׁשְּׁנֵיהֶם צַדִּיקִים; אֲבָל כָּאן אֶחָד צַדִּיק וְאֶחָד רָשָׁע:
והנה תומם BEHOLD, THERE WERE TWINS — The word for twins is written defective (without א and י) whilst in the case of Tamar it is written תאומים (with א and י); because in the latter case both children proved righteous whilst here one was righteous and the other wicked (Genesis Rabbah 63:8).
וְאַֽחֲרֵי־כֵ֞ן יָצָ֣א אָחִ֗יו וְיָד֤וֹ אֹחֶ֙זֶת֙ בַּעֲקֵ֣ב עֵשָׂ֔ו וַיִּקְרָ֥א שְׁמ֖וֹ יַעֲקֹ֑ב וְיִצְחָ֛ק בֶּן־שִׁשִּׁ֥ים שָׁנָ֖ה בְּלֶ֥דֶת אֹתָֽם׃
Then his brother emerged, holding on to the heel of Esau; so they named him Jacob. Isaac was sixty years old when they were born.
ואחרי כן יצא אחיו וגו'. שָׁמַעְתִּי מִ"אַ הַדּוֹרְשׁוֹ לְפִי פְּשׁוּטוֹ, בְּדִין הָיָה אוֹחֵז בּוֹ לְעַכְּבוֹ, יַעֲקֹב נוֹצַר מִטִּפָּה רִאשׁוֹנָה וְעֵשָׂו מִן הַשְּׁנִיָּה; צֵא וּלְמַד מִשְּׁפוֹפֶרֶת שֶׁפִּיהָ קְצָרָה, תֵּן לָהּ שְׁתֵּי אֲבָנִים זוֹ אַחַר זוֹ – הַנִּכְנֶסֶת רִאשׁוֹנָה תֵּצֵא אַחֲרוֹנָה וְהַנִּכְנֶסֶת אַחֲרוֹנָה תֵּצֵא רִאשׁוֹנָה; נִמְצָא עֵשָׂו הַנּוֹצָר בָּאַחֲרוֹנָה יָצָא רִאשׁוֹן וְיַעֲקֹב שֶׁנּוֹצַר רִאשׁוֹנָה יָצָא אַחֲרוֹן, וְיַעֲקֹב בָּא לְעַכְּבוֹ, שֶׁיְּהֵא רִאשׁוֹן לְלֵדָה כְּרִאשׁוֹן לִיצִירָה, וְיִפְטֹר אֶת רַחְמָהּ וְיִטֹּל אֶת הַבְּכוֹרָה מִן הַדִּין:
ואחרי כן יצא אחיו וגו AND AFTERWARDS HIS BROTHER CAME OUT, ETC. — I have heard a homiletical midrash that expounds it according to its simple meaning: It was with justice that he was grabbing him to hold him back. Jacob was conceived from the first drop and Esau from the second. Go and learn from a tube with a narrow opening - put in it two stones, one after the other. The one that goes in first will come out last, and the one that goes in last will come out first. It comes out that Esau, who was conceived last, came out first, and Jacob, who was conceived first, came out last. And [so] Jacob came to hold him back, so that the first for birth would be the same as the first for conception; and he would open [his mother's] womb and take the first-born status with justice (see Genesis Rabbah 63:8).
appears to be an abbreviation for "from an aggadah"