כלאים. חִטָּה וּשְׂעוֹרָה וְחַרְצָן בְּמַפֹּלֶת יָד (ברכות כ"ב): כלאים [THOU SHALT NOT SOW THY VINEYARD] WITH DIVERSE KINDS OF SEEDS — i.e. wheat and barley together with kernels of grapes with one and the same hand-throw (Berachot 22a; Kiddushin 39a; Chullin 82b).
פן תקדש. כְּתַרְגוּמוֹ "תִּסְתָּאַב", כָּל דָּבָר הַנִּתְעָב עַל הָאָדָם, בֵּין לְשֶׁבַח כְּגוֹן הֶקְדֵּשׁ, בֵּין לִגְנַאי כְּגוֹן אִסּוּר, נוֹפֵל בּוֹ לְשׁוֹן קִדּוּשׁ, כְּמוֹ "אַל תִּגַּשׁ בִּי כִּי קִדַּשְׁתִּיךָ" (ישעיהו ס"ה): פן תקדש LEST IT BECOME קדש — Take it as the Targum does: lest it become unclean (unfit for use); to anything for which a man has repugnance to come into contact with, be it on account of its sublimity as, for instance, holy things, or be it on account of some bad quality, as, for instance, something that is forbidden, the term קדוש is appropriate, as, in the latter sense, e.g., (Isaiah 65:5) “Come not near to me for I make thee קדוש".
(המלאה. זֶה מִלּוּי וְתוֹסֶפֶת שֶׁהַזֶּרַע מוֹסִיף): [המלאה — This is the fullness and increase which the seed produces].