Babylonian Talmud, Kiddushin 71a
תלמוד בבלי קידושין עא.
א"ר יוחנן היכלא בידינו היא אבל מה אעשה שהרי גדולי הדור נטמעו בה סבר לה כר' יצחק דאמר ר' יצחק משפחה שנטמעה נטמעה
Rabbi Yohanan said: I [swear] by the Sanctuary that it is in our power [to reveal which families in the Land of Israel are genealogically tainted]! But what can I do? For behold, great people of the generation are mixed with them! Rabbi Yohanan agrees with Rabbi Yizchak, for Rabbi Yitzchak has said [once a genealogically tainted] family is mixed, it is mixed. [Translation by Rabbi Steve Greenberg]
Time Period: Rabbinic (Maccabees through the Talmud)